Musculoskeletal Research

Gwendolyn Sowa, MD, PhD, focuses her research in deciphering the biology of intervertebral disc degeneration (IDD) and subsequent development of biological and biomechanical therapies guided by the basic science of the disease process. She currently performs molecular laboratory based, translational, and clinical research, investigating the effect of motion on inflammatory pathways and the beneficial effects of exercise.Projects include:

  • Alternative treatments for disc degeneration: effects on matrix homeostasis
  • Comparison of manual vs. mechanical chiropractice manipulation methods
  • Identification of biomarkers predictive of response to spinal injections

Fabrisia Ambrosio, PhD, MPT, using pre-clinical and clinical models, her research implements molecular, cellular, and functional analyses to investigate the development of approaches to both harness our body’s natural healing capacity and enhance the functional efficacy of regenerative medicine technologies. Projects include:

  • Electrical stimulation reverses the effect of age on skeletal muscle
  • Mechanical loading as a critical determinant for functional skeletal muscle formation with a biological scaffold

Kentaro Onishi, DO, focuses on translational research in the domain of musculoskeletal regenerative medicine and tendon injuries.